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Individuals whose gestation coincided with the famine exhibited increased susceptibility to obesity, insulin resistance, and cardiovascular disease in adulthood, strongly implicating fetal adaptive responses to nutrient scarcity in shaping lifelong disease risk [10,11]

In this Review, we systematically characterizes the molecular architecture underlying ferroptosis, focusing on its core machinery governing iron homeostasis and lipid peroxidation, as well as the principal antioxidant defense systems that counteract this process

The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling

Statistical analysis Results are presented as the mean standard deviation (SD)

therefore, passive targeting exploits this effect and tumor characteristics to enrich drugs for liver tumors [60, 61]