melanotic coli Abuse of laxatives and melanosis Melanosis coli is dark brown-black

Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association Melanosis Coli Gastroenterology & Hepatology of CNY Melanosis Coli Benign Discoloration Poses Questions MELANOSIS COLI** Melanosis coli is a disorder of pigmentation of the bowel wall. Histology demonstrates pigment laden macrophages It is associated with laxative abuse, especially **anthraquinone compounds such as senna**

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