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In the largest trial conducted so far, a phase 2 study involving 706 overweight or obese participants, side effects were common across all dosage levels, ranging from 0.3 to 4.5 mg/week [11]

Other commonly reported effects include: Temporary fatigue (first few days) Occasional digestive discomfort Mild headache These effects usually resolve on their own and decrease with consistent use

A more significant injury such as a Grade 3 sprain can take several months

Common side effects include nausea, mucositis, liver toxicity, and bone marrow suppression, necessitating close monitoring during treatment

Historically states have had limited ability to use Medicaid to help address social determinants of health