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Instead, GABA production occurs by utilizing glutamate in neurons

However, the harmful effects of excessive trace elements are still not completely understood

Although they can both regulate cell apoptosis and cell cycle, cisplatin induces a large number of genes related to DNA damage, P53 and apoptosis, while some ruthenium complexes facilitate the expression of oxidative stress and ER stress ( The existing research achievements should be combined with molecular biology and nanomaterials, applying the advantage of existing tools and methods to develop antitumor drugs with better therapeutic effects, based on these complexes

Acknowledgements The authors gratefully acknowledge Mehdi Damaghi for the tumor spheroid model graphic (Figure 1A) and Mark Lloyd for the digital pathology graphic (Figure 1B)

doi: 10.1002/jnr.21483 135 LiuWLiYJalewaJSaunders-WoodTLiLHlscherC