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Because of the increasing importance of phycoremediation strategies, the development of strains that can tolerate high HM concentrations is of primary importance, and biotechnological research in the coming years is likely to focus on increasing MT and PC content of microalgae

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Abbreviations DEPs: differentially expressed proteins DIMBOA: 2,4-dihydroxy-7-methoxy-2 H-1,4-benzoxazin-3(4 H )-one GST: glutathione S -transferase iTRAQ: Isobaric Tags for Relative and Absolute Quantitation qPCR: quantitative PCR References Zhang Z, Gu T, Zhao B, Yang X, Peng Q, Li Y, Bai L