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Ahuja S, Brendle M, Smart L, et al

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Dysregulation of the UPS and interferon-beta (IFN-) signaling contributes to MS development, making UPS components potential therapeutic targets

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doi:10.1371/journal.ppat.1010670

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Cell viability was assessed 3 days after treatment with FOXO4-DRI at 0, 12.5, 25, 50, and 100 M, respectively, using the Cell Counting Kit-8 (CCK-8) Assay (Dojindo, Rockville, MD, United States)

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It's a primary regulator of actin, a protein that is fundamental to cell structure, movement, and division

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