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SV: editing and revising manuscript critically for intellectual content

The impact of E-cigarettes on the lung and health affects are explained below, including the potential for DNA damage as a result of exposure to toxic substances in vaping products: Diseases caused by E-cigarettes /Vaping E-cigarette Vaping product use Associated Long Injury (EVALI) 19 Vaping Associated Pulmonary Injury (VAPI) 19 Death due to inability to breathe (EVALI) 19 Bronchiolitis obliterans also known as popcorn lung 7 Long-term scarring of the lungs 3, 18 Respiratory distress and disease 7 Asthma 11, 12 Heart Attacks 8 Damage to the liver, kidney and nervous system 14 Eye, nose and throat irritation 14 Headaches and nausea 14 Bronchiolitis obliterans also known as popcorn lung This is a condition that damages the small airways of the lungs resulting in coughing and shortness of breath

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Garlic, onions, and cruciferous vegetables provide the necessary sulfur compounds, while high-quality whey protein or bone broth can supply the amino acids (like cysteine) required for its synthesis

These effects are particularly evident in patients with obstructive sleep apnea (OSA), where chronic intermittent hypoxia leads to sustained activation of the HIF-1/NF-B axis, promoting inflammation, increased sympathetic activity, and systemic hypertension [55,56]