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Mechanistically, selenium deficiency may exacerbate thyroid-related neurological dysfunction through three pathways: impaired deiodinase activity, weakened antioxidant defense, and disrupted selenium transport (134136)

According to a study published in Frontiers in Pharmacology, intramuscular administration of vitamin B12 produces a faster increase in serum levels compared to oral routes, although both methods are effective in restoring normal cobalamin levels in patients with deficiency

10.1007/s11738-015-2023-4 Acta Physiol

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