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Hallmarks of trained immunity at the HSC level include increased HSC proliferation, expansion of myeloid-biased multipotent progenitor 3 (MPP3), and myeloid-biased differentiation 14,15

doi: 10.1016/j.ejca.2024.115069 304

[130] demonstrated that, compared with SCIT, ITIT has superior efficacy, a lower dosing frequency, and an elevated population of Treg and TFR cells in patients with AR

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On lung tissue of mice fed low-dose arsenic, changes in extracellular matrix (ECM) protein expression and a large increase in matrix metalloproteinase (MMP)-9 expression were revealed [21]