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& Botelho, R

Although the exact mechanism leading to this outcome is undetermined, gene susceptibility and brain infection by several microorganisms has been associated with the pathogenesis of AD, such as for Chlamydophila pneumonie (Grard et al., Borrelia burgdorferi (Miklossy, 2011) and HSV-1 (Itzhaki, 2014, 2016), among others (Lurain et al., 2013

Molecular Autism , 7 (1), 26

Vitamin D has been discovered to decrease cytokine synthesis in immune cells

Additionally, pioglitazone improves glucose metabolism in spermatogonial stem cells by enhancing glycolysis and lactate production, making it effective in treating diabetes-induced spermatogenic disorders [354]