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We observed that a decrease in the epithelial marker cadherin 1 (CDH1) (Supplementary 5A,B) and a significant increase in mesenchymal markers like smooth muscle actin (ACTA2) and Vimentin, particularly in the TC THP1 model, indicating enhanced EMT in response to CS exposure (Supplementary Fig

The most studied and controversial target is SLC3A2, which can mediate the export of spermidine, spermine, and putrescine in colonic epithelial cells, as well as the extracellular release of the polyamine metabolic intermediate N1-acetylspermidine in liver cancer cells [290, 291]

Dhner, H

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Main Research Findings 1) Dihexa has therapeutic potential to act as a treatment for various neurological disorders related to reduced synaptic connectivity, such as Alzheimers disease