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Furthermore, CSC induced an imbalance in the gut bacterial community and heightened susceptibility to bacterial infection-induced ileal damage in mice

Deletion of nuclear factor ImerC (NFI-C) leads to overexpression of plasminogen activator I (PAI-1) and subsequent inhibition of uPA activity and HGF signal, thus impairing hepatocyte proliferation (Marubashi et al., 2004)

LC-MS-TOF, Liquid chromatography time-of-flight mass spectrometry

To explain this decrease in cell viability, cell cycle and apoptosis analyses were performed

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