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Interestingly, omega-3 PUFAs were evaluated in rat models of intestinal damage by MTX, and this study demonstrated that omega-3 PUFAs exhibited the ability to prevent intestinal damage and stimulate intestinal recovery

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The expression level of SIRT3 in patients with gallbladder cancer (GBC) is notably lower compared to adjacent normal tissues, and low expression of SIRT3 is positively associated with poor overall survival

The theory is strong, the lab data convincing, but large-scale, rigorous clinical trials are still missing

doi: 10.1038/jid.2011.109 256 Rodrguez-ArmbulaATorres-lvarezBCorts-GarcaDFuentes-AhumadaCCastanedo-CzaresJP