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Amy Fluitt email: [email protected] phone: 310-825-8922 office: 220C Hershey Hall Research Interests Selected Publications Dr

Caffeine Directly Binds to SIRT3 to Enhance Its Substrate Binding Affinity SIRT3 is an NAD + -dependent deacetylase that transfers ADP-ribose from NAD + to a substrate and the acetyl group on the substrate lysine residue to generate nicotinamide (Scher et al., 2007)