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In addition to eliminating diseased target cells, cisplatin can damage normal cells

Poor diet: Inadequate consumption of fruits, vegetables, and sulfur-rich foods leads to the reduction of glutathione

Whereas, EAATs decrease extracellular L-glu, extracellular cerebral L-glu is upregulated in different brain regions by the cystine/glutamate antiporter system x (De Bundel et al., 2011