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Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study

Ann Surg 2010;252:591-596

According to a 2023 study[1] published in the journal, Dermatology Online , There are a number of reports on the onset of acute annular pustular psoriasis with the COVID-19 vaccine as well the development of pustular psoriasis in a patient with established plaque psoriasis following the administration of the vaccine It has been suggested that certain cutaneous COVID-19 vaccine reactions may represent unmasking of subclinical inflammatory dermatoses due to the immune boosting properties of the vaccine

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The short of it is that fatigue and reduced athletic performance isnt driven so much by muscle glycogen depletion as it is, likely, from a central nervous system mechanism that can be hacked by just giving a tiny bit of carbs during very high intensity exercise to keep the blood supply from dropping the carb equivalent of ~1/2 tsp of honey per 20 min of intense exercise