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10.3389/fmicb.2023.1114707 106 NieK.MaK.LuoW.ShenZ.YangZ.XiaoM.et al

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Hepatic Metabolism and Mechanism(s) of Toxicity Following therapeutic administration of APAP, approximately 25% of dose is undergoes first pass metabolism, with the liver playing a primary role (37)

After epileptic seizures were induced by pentylenetetrazole, the expression of 5-HT3 was upregulated, and the level of GABA B was downregulated

Children aged 412 years were diagnosed with ASD according to DSM criteria, both boys and girls were included, and the study explicitly excluded participants with major psychiatric comorbidities such as ADHD, depressions, bipolar disorder, anxiety disorders, epilepsy, severe intellectual disabilities, or recent antipsychotic use, ensuring relative homogeneous sample focused on irritability