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The LPS is a surface membrane component of gram-negative bacteria and is recognized by toll-like receptor 4 (TLR4) on the membranes of intestinal epithelial cells, which stimulates components of the immune system [67]

Oxaloacetate treatment for mental and physical fatigue in myalgic Encephalomyelitis/Chronic fatigue syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial