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Description

In this study, we investigated the effects of dysregulated glutathione homeostasis, a principal feature of oxidative stress, on TNF-induced hepatotoxicity and its mechanistic implications in NAFLD progression

Anticancer Res 2005

Vitamin C is also an active antioxidant

By accurately identifying high-risk populations through patient stratification tools, this approach reduces the number needed to treat (NNT), minimizes patients' exposure to unnecessary pharmacological toxicity, and effectively lowers the population-level incidence of cardiovascular diseases, while simultaneously optimizing the allocation of healthcare resources (206)