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By integrating CT/magnetic resonance (MR) dual-modality imaging, photothermal/photodynamic responsiveness, drug-loading capability, and effective embolization, these microspheres achieve precise image-guided and laser-enhanced chemoembolization

RNA was precipitated with isopropanol and collected by centrifugation at 12,000 g for 15 min at 4 C

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The exquisite immune specificity for beta cells suggests that such cells may already harbour molecular signatures of vulnerability, which may act not only as initiators or conduits for the early immune response but also as amplifiers of ongoing beta cell-directed immune destruction (Kracht et al