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Agathisflavone has been found to significantly increase the number of neuronal progenitor cells and mature neurons without increasing astrocytes or microglia, and also to effectively reduce the inflammatory factors factor-, interleukin-6, interleukin-1, NO, and PGE2 ( in vitro and enhances the neuroprotective properties of microglia and astrocytes

Beyond innovative microsurgical methods that, in certain cases, are necessary to repair nerve injuries, different nonsurgical treatment approaches and adjunctive therapies have been investigated to enhance nerve regeneration

Cointervention All pregnant women will also be given folic acid (0.4 mg) for the first 2 months of pregnancy followed by iron (60 mg elemental iron) and calcium supplements (500 mg) until 45 days after delivery according to the WHO guidelines.30 Recruitment procedure, confirmation of pregnancy and assessment of gestational age Prior and throughout the study period, we will identify pregnant mothers through a hospital and community-based surveillance system (figure 1)

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