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The supernatant was then applied to nickelnitrilotriacetic acid (NiNTA) agarose resin (Fujifilm), for purification according to the manufacturers protocol

Zhu, W., Cremonini, E., Mastaloudis, A

If semaglutide (single agonist) is first generation, and tirzepatide and mazdutide (dual agonists) are second generation, then retatrutide (triple agonist) is the beginning of the third generation

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