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1-3 Glutathione is also involved in the metabolism of certain compounds that can increase free radical activity

and optineurin (OPTN), a mitophagy receptor with mutant isoforms observed in glaucoma patients (Rezaie et al., 2002)

Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy

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