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Given the striking impact of GLUT3 deficiency on M2 polarization in vitro, we next investigated its effect on macrophage function in vivo

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Kuwabara et al., 2018 treated bronchoalveolar (BAL) tissue of Goto-Kakizaki (GK) and High Fat Diet (HFD) mouse with LPS and demonstrated an impaired in the chemotactic property of neutrophils, decrease in the neutrophil count, reduced release of IL-1, IL-6, TNF- and MPO activity along with an increase in CXCL3 levels

It has been observed that the inhibition of NBT reduction is typically more pronounced than the inhibition of cytochrome c reduction (Aruoma et al