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In a perfusion chamber, we monitored the response of HeLa cells to stepwise increases in H 2 O 2 concentration ( Figure 2G )

There are eight types of GPX family in mammals (GPX1, GPX2, GPX3, GPX4, GPX5, GPX6, GPX7, GPX8), of which GPX1-4 and GPX6 of mammals are considered to be selenoproteins containing selenium, which have antioxidant functions, and GPX6 is only expressed in the human body ( In mammals, GPX works with superoxide dismutase and catalase to form an enzymatic antioxidant system that reduces reactive oxygen species (ROS) and limits their toxicity

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It has a sequence of Gly-His-Lys (glycine, histidine, and lysine,) which readily binds with copper to form the copper tripeptide

Evaluation of a spectrophotometric assay for the measurement of malondialdehyde and 4-hydroxy-alkenals in human spermatozoa: relationships with semen quality and sperm function