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These changes may include increasing arterial stiffness, reduced elasticity, impaired function of the blood-vessel lining, chronic inflammation, and the development of atherosclerotic plaque

Cover: Miguel Gandert, Hermann Strohbach

Lieberman P

there are little data on the safety of continued use of these agents in patients who develop an infection while on therapy, although anecdotal evidence suggests that they can safely be restarted in many cases after the infection has resolved