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Combined blockade of IL6 and PD-1/PD-L1 signaling abrogates mutual regulation of their immunosuppressive effects in the tumor microenvironment

One of these directions has focused on investigating the occurrence of abnormal or increased cell death and the inadequate clearance of dead cells that leads to the release of the intracellular contents from the dead cells to trigger inflammatory reactions

Fluorescence images were acquired using an inverted fluorescence microscope

Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly and axon degeneration

Cancer Cell (2019) 35(5):752766.e759