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Moreover, abnormalities in this axis and in cortisol levels can be related to higher cardiovascular risk [164, 165], which may explain the increase in the mortality rate and in the cardiovascular risk factors prevalence observed in affective disorders, including BD [166]

But food alone cannot reliably restore levels once demand outpaces supply

Farhadi, A., Vosough, M., Zhang, J

Most side effects from B12 shots resolve quickly, making them generally well-tolerated for routine supplementation

Nusrat M, Roszik J, Katkhuda R, Menter D, Raghav KPS, Morris VK, Sharma P, Allison JP, Blando JM, Maru DM, Overman MJ, Kopetz S