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Published online 2017 Jan 1

In a small study of 21 healthy-weight individuals who consumed a MedDiet for 3 days, then a Canadian diet [reflecting the average Canadian dietary intake, which would be considered a Western diet (180)] for 13 days, followed by a MedDiet for an additional 3 days, circulating SCFAs and branched-chain fatty acids were not significantly altered by the first MedDiet intervention, but propionate, valerate, isobutyrate, and isovalerate were increased by the Canadian diet, then decreased after the second MedDiet (65)

After oral administration, blood samples were collected at 2, 4, 6, 8, and 24 hours timepoints with 2 ml/timepoint