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Additionally, inhibition of PKC was shown to reduce NRF2 phosphorylation and transcriptional activity, along with the expression and activity of NRF2-regulated antioxidant proteins [43]

Fortunately for them, unfortunately for the research committee, their skulls were intact so they couldn't measure directly in the brain

(1995) 61:1402S6S

Collectively, these findings indicate that suppression of leukocyte recruitment represents a functionally independent mechanism of renoprotection that complements endothelial CAM inhibition