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We have recently found that inhibiting the ADM/NO signaling pathway can indeed reduce the neuronal pathology in early DR

Importantly, we found that MM patients with upregulated METTL5 expression had a poorer prognosis

defined as partial Mayo score 2 without steroids) at week 12, endoscopic remission (CFREM + endoscopic Mayo score 1) at week 12, time to first biologic discontinuation, time to first hospitalization and time to colectomy