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FRCs from the spleen or lymph nodes were isolated by enzymatic digestion as described previously 55

Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression

Glutamate-cysteine ligase protects cells from ferroptosis by decreasing glutamate levels, converting them to -glutamyl peptides, and boosting GSH production (36) ( Figure 1 )

Taken together, these results suggested that redox control pathways in subcellular compartments are separately and precisely controlled to meet the specific redox requirements in these distinct locations.