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The Role of Ferroptosis in Cancer Development and Treatment Response

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Future investigations should prioritize delineating the underlying molecular and cellular mechanisms, refining formulation and delivery platforms to overcome bioavailability constraints, and implementing rigorously designed, adequately powered clinical trials across diverse populations

Regulation via enzyme synthesis or degradation takes even longer, on the order of hours

Copper toxicity and deficiency: the vicious cycle at the core of protein aggregation in ALS