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The pharmacological interventions restored the GABA/glutamate balance by increasing GABA levels while decreasing glutamate concentrations

Its overexpression in different subcellular compartments defends cells against death provoked by nitro-oxidative stresses, while its silencing makes the cells more susceptible to oxidative damage and apoptosis (122)

Addressing all these challenges requires significant investment in healthcare infrastructure, including the expansion of endoscopic services, training of healthcare providers, including physicians, nurses, pharmacists, etc., and improved access to diagnostic and monitoring tools

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