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Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13

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Furthermore, blocking BDNF abolished the antidepressant-like effects of fucoidan in mice, indicating that fucoidan ameliorates depression by inhibiting inflammation and modulating synaptic plasticity (Li et al., 2020)

As awareness of acute intermittent porphyria increases among healthcare professionals and patients, clinics are becoming more involved in the early detection and diagnosis of the disorder