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Description

Florian Greten at the Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, the trial examined whether 1,000 mg/day of Mitopure could improve markers of immune fitness, immune cell metabolism, and mitochondrial function

Importantly, blocking TFRC/CD71 with specific antibodies significantly reduced ferroptosis induction by ML162, suggesting that the ibrutinib effect could be at least partially explained by its ability to modulate TFRC/CD71 (Supplementary Fig