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FIGURE 3 Nuclear factor-erythroid-derived 2-like 2 (NFE2L2, also named Nrf2) is a transcription factor which plays a crucial role in resistance to oxidative stress (Ma, 2013)

on the other hand, it promotes transcriptional expression of GPX4, protecting cells from OS and inhibiting ferroptosis (Chen et al., 2020b)

10.1186/s13073-021-00920-z 106 GeoergerB.ChisholmJ.Le DeleyM

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