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Low serum IGF-1 may contribute to treatment resistance (Treb, 2017), but most AGA patients have normal systemic IGF-1 levels

Increased oxidative stress, as observed in asthma and other inflammatory diseases, leads to a drop in the concentration of antioxidant vitamins such as vitamin C or E

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GHK-Cu stimulates fibroblaststhe cells responsible for producing collagen and elastinhelping to restore skin structure and reduce visible signs of aging

The high insulin levels could probably cause a downregulation of IGF-I production by the liver and other tissues, as a compensatory homeostatic mechanism, induced most likely through a differential modulation of IGFBPs production