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Furthermore, we discuss various small-molecule inhibitors targeting ferroptosis, categorized by their mechanisms of action, including iron chelators, lipid peroxidation inhibitors, antioxidants, and regulatory pathway modulators

10.1016/j.lfs.2020.118660 94 Guerrero-MauvecinJ.Villar-GmezN.Rayego-MateosS.RamosA

503,504 Antioxidants ALA is a potent antioxidant that mitigates oxidative stress, a key contributor to DN, inhibits lipid peroxidation, improves endoneurial blood flow, and enhances nerve glucose uptake and energy metabolism