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In addition, although the L-carnitine group demonstrated numerically higher baseline LTI values, no statistically significant differences were observed between the study groups at baseline, suggesting the absence of a meaningful baseline imbalance

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Oxidative stress can render tumor cells insensitive to anti-proliferative signals, apoptosis, and anchorage-independent growth, which alters tumor cell invasion and migration through epigenetic and metabolic mechanisms, further contributing to colorectal cancer development and progression (Ziczuk et al., 2020)