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These apoptotic processes involve the activation of cysteine-aspartic proteases, such as caspases and calpain, which are activated by the interactions of various neurochemical, cellular, and molecular pathways, including ERK, p38 MAPK, and JAK/STAT (Thapa et al., 2021)

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The self-healing ability and pH/ROS responsiveness of multifunctional glycopeptide EPMA hydrogel as a wound dressing enhanced skin tissue regeneration and wound repair with multifunctional biological activities, including anti-inflammatory, anti-bacterial, and angiogenesis activation as well as macrophage polarization regulation