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Cagrilintide binds to the calcitonin receptor and all three amylin receptors (AMY 1 , AMY 2 and AMY 3 receptors) [6]

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In ongoing phase 3 clinical trials, dosing starts at 0.25 mg per week alongside semaglutide, with gradual increases reaching a maximum of 2.4 mg weekly by the 17th week, following a 16-week dose-escalation protocol [16]

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OSullivan ED, Hughes J, Ferenbach DA

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