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The intrinsic pathway is activated by the oligomerization of the BCL2 family protein BAK and BAX, which contributing to the formation of oligomers from pores in the mitochondrial outer membranes, leading to the release of cytochrome c into the cytosol

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Among these, colistimethate sodium and tobramycin are the most widely prescribed, supported by the strongest evidence base and longest clinical experience [9,10]

She also serves as an executive member of the Nursing Committee of the Inflammatory Bowel Disease Specialty Committee of the China Medical Pharmaceutical Education Association