interaction of chloroacetamide electrophiles with cellular glutathion

interaction of chloroacetamide electrophiles with cellular glutathion Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability Characterization of glutathione proteome in

Name: interaction of chloroacetamide electrophiles with cellular glutathion Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability Characterization of glutathione proteome in
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Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis Chevallier 2020 Biotechnology and Bioengineering Wiley Online Library The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Glutathione Transferases: Potential Targets to Overcome Chemoresistance in Solid Tumors Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines Journal of Medicinal Chemistry Dual inhibition of carbonic anhydrase IX and glutathione peroxidase 4 as a novel strategy for ferroptosis induced tumor cell death ScienceDirect

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Glutathione is naturally found throughout the body and is especially important in areas such as the liver, brain, lungs, heart, kidneys, skin and eyes

10.1016/j.psyneuen.2011.04.012 6 AsadiS.GholamiM

Cancer Res 56:36783681 Gundimeda U, Schiffman JE, Chhabra D, Wong J, Wu A, Gopalakrishna R (2008) Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells