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Alomari, M

Our results revealed that oxidative stress-related pathways, including glutathione (GSH) metabolism, were significantly enriched in the auditory cortex of mice exhibiting tinnitus-like behavior

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In contrast, mitochondrial PRDX3 undergoes hyperoxidation during lipid peroxidation stress and translocates to the plasma membrane, where it suppresses cystine uptake, depletes intracellular GSH, and amplifies ferroptotic execution 114

Binding of AIM to Fc/J was performed with the same protocol in the presence of 2.0 mM of various divalent cation chlorides (CaCl 2 , MgCl 2 , MnCl 2 , CoCl 2 , NiCl 2 , ZnCl 2 ) in triplicate wells in a single experiment