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Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells

Apigenin displays antioxidant activity through inhibition of pro-oxidant enzymes, modulation of redox signaling pathways (NF-B, Nrf2, MAPK, and P13/Akt), reinforcing enzymatic and non-enzymatic antioxidants, metal chelation, and free radical scavenging [171]

From models to humans: external validity Rodent phenotypes often reflect housing, diet and circadian conditions that reshape redox tone

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