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Succinate is an inflammatory signal that induces IL-1 through HIF-1

The quest for better sleep can sometimes feel overwhelming, but what if the answer lies in a little-known antioxidant called glutathione

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After removal of the overlying meninges and blood vessels, spinal cords were cut into small pieces, dissociated with 0.05% collagenase I (Thermo Fisher Scientific, Foster City, CA, USA) for 15 min at 37 C, and then processed to produce epSPC neurospheres as previously described 6,18