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MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1

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In the non-tumorigenic 21NT line the effect tracked an approximately 12-fold upregulation of hTERT mRNA at 1 g/mL, whereas in BT-474 (a tumour line lacking conventional telomerase reactivation in their assay system) telomere elongation appeared to occur via the alternative lengthening of telomeres (ALT) pathway

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GSK-3 plays important roles in various tissues, and its peripheral effect should be considered before applying GSK-3 inhibitors for AD treatments clinically