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[DOI] [PubMed] [Google Scholar] 407

A phase 2 human trial was completed in 2009 and never published

Statistical significance is denoted by asterisks in Figs

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34 In clinical studies involving both animals and humans, a special preparation of Coleus forskohlii, applied directly to the eye, was shown to reduce IOP by increasing intraocular circulation and decreasing aqueous humor inflow into the posterior cavity