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Ustione, A., Piston, D

Nature, 605 (7911), 747753

We generated Gpx1 lox/lox mice to conditionally delete Gpx1 in hepatocytes ( Alb - Cre

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and GOx) employs a two-step cascade reaction to generate potent -OH radicals in acidic environments, achieving 4-fold enhanced catalytic efficiency in disrupting S